PT-141, also known as Bremelanotide (brand name Vyleesi), is a peptide therapy designed to address sexual dysfunction in both men and women. Unlike traditional treatments that focus on the vascular system, PT-141 works by activating melanocortin receptors in the brain, which play a crucial role in sexual arousal and desire. This mechanism allows it to effectively enhance libido and sexual satisfaction. In clinical studies, PT-141 has shown significant improvements in sexual desire and related distress in individuals with hypoactive sexual desire disorder (HSDD).